The level of alcohol consumption and drug abuse, particularly among the youth, is of national concern. From 2000 to 2005 the number of patients admitted with substance misuse at the psychiatric ward at Victoria Hospital increased by 22.6%. In 2005 70.3% of all admissions were attributed to substance abuse compared to 59.3% in 2000.

Seychelles ratified the Framework Convention on Tobacco Control (FCTC) in 2003, a treaty that aims at stimulating and harmonizing national legislation for tobacco control. The Seychelles Bill for Tobacco Control has been drafted. The Bill constitutes a comprehensive legislation that follows sound public health principles and addresses most of the obligations under the Framework Convention.